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At our 39 testing facilities around Overton, Texas, Accredited Drug Testing offers a wide array of drug and alcohol testing services. We conduct both DOT and non-DOT urine drug screenings, breathalyzer tests, EtG tests for alcohol, and hair follicle drug analyses serving personal, business, and legal requirements. Rapid results and SAMSA-certified lab reviews are available in Overton, TX, with quick service options—most testing centers are conveniently located near your residence or workplace. Supplementary services include Occupational Health Assessments, Clinical Diagnostics, and Background Verifications.
To schedule a test, dial (800) 221-4291 or register by visiting our online portal. Select your desired test type and a convenient location—testing services are provided for you, your staff, or others. Arranging tests is efficient and straightforward; contact our scheduling team or use our 24/7 online booking system. Our seamless and intuitive setup allows you to coordinate drug assessments near Overton with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Overton drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
A 2019 survey revealed that Rusk County, where Overton, TX is located, had a 15% higher rate of prescription drug misuse compared to the national average.
In 2021, Overton saw a 25% increase in opioid-related hospitalizations, indicating a growing concern in the community.
Methamphetamine-related incidents accounted for 30% of all drug-related arrests in Overton during 2020.
Among students in Overton Independent School District, 18% reported trying marijuana at least once, as per a 2020 report.
The number of overdose deaths in Rusk County increased by 40% from 2017 to 2022, with a significant portion occurring in Overton.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Overton, TX are keenly aware of the challenges posed by drug abuse and have implemented strict drug testing policies to ensure a safe workplace. Regular and random drug testing is common, particularly in sectors such as transportation and public safety. Employers frequently coordinate with the Texas Workforce Commission (TWC) for guidance on best practices.
Many local businesses participate in drug-free workplace programs sponsored by the Texas Department of Licensing and Regulation (TDLR). These initiatives not only aim to maintain a healthy work environment but also provide assistance for employees struggling with substance abuse, offering them access to confidential counseling services.
The city of Overton, TX, in collaboration with Rusk County, has implemented several initiatives to combat drug problems. Programs focused on public awareness and prevention have been a priority. These include educational workshops in schools and partnerships with local law enforcement. The Rusk County Substance Abuse Coalition is actively working to create a drug-free environment through community engagement.
State resources also play a role in addressing these issues. The Texas Department of State Health Services (DSHS) offers support through various substance abuse prevention programs, while federal funding helps bolster local efforts. Outreach programs funded by National Institute on Drug Abuse (NIDA) assist in research and strategy development for effective intervention.
In recent years, Overton, TX has seen several high-profile drug busts. In early 2022, local law enforcement conducted a significant operation leading to multiple arrests related to a methamphetamine distribution ring. This was a combined effort with the Rusk County Sheriff's Office, emphasizing the region's commitment to cracking down on illegal drug activities.
Community events focused on drug awareness are also a regular occurrence in Overton. These include annual forums sponsored by local schools and the Rusk County Health Department, which aim to educate residents about the dangers of drug usage. Such initiatives are crucial in efforts to engender a collective response against drug abuse.
Accredited Drug Testing offers fast, reliable employment screening services in Overton, TX. Trusted by employers nationwide for accurate results and exceptional service.
Meadows Mental Health Policy Institute
Texas Substance Abuse Prevention
Texas Medical Association
Substance Abuse and Mental Health Services Administration
Partners Resource Network
Helpline Center
Recovery Resource Council
Dallas County Behavioral Health Leadership Team
Office of the Texas Attorney General
BCFS Health and Human Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024