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At 35 testing centers in the South Plains, Texas region, Accredited Drug Testing delivers a full range of drug and alcohol screening services. We administer both DOT and non-DOT urine tests, breathalyzer tests, EtG tests, and hair follicle drug tests for personal, employment, and legal purposes. Our rapid results service is quick and most South Plains testing centers are conveniently located close to you for same-day appointments. Accredited Drug Testing also specializes in Occupational Health Testing, Clinical Testing, and Background Checks to cater to your needs.
To schedule a test, either call (800) 221-4291 or register through our online platform. Select the specific test you need and pick an accessible location. Whether it's for yourself, your employees, or another individual, testing is designed to be Simple and Convenient. Our efficient scheduling system allows you to book your test by phone or online anytime. Organizing a nearby drug test in South Plains is now almost effortless thanks to our intuitive process.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our South Plains drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2023, Lubbock, TX, experienced a 15% increase in drug-related arrests, highlighting a rise in substance abuse issues across Lubbock County.
The South Plains region reported a 25% surge in fentanyl overdoses in 2022, causing concerns among public health officials in Lubbock County.
A 2022 survey in South Plains, TX, revealed that 20% of high school students in Lubbock County had experimented with illicit drugs.
Methamphetamine remains the most commonly abused drug in South Plains, TX, with Lubbock County reporting a 10% rise in seizures in 2022.
Lubbock County recorded a 30% increase in admissions to drug rehabilitation centers in South Plains, TX, from 2021 to 2022.
In 2023, Lubbock County law enforcement reported a significant uptick in drug-related thefts across the South Plains area.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in South Plains, TX, are increasingly implementing drug testing policies to ensure a safe and productive work environment. Many local businesses participate in the U.S. Department of Labor's Drug-Free Workplace Program, which outlines guidelines for maintaining a drug-free workplace.
Regular drug screenings are conducted as part of pre-employment requirements and ongoing employment. These policies aim to decrease workplace accidents and improve overall employee health in Lubbock County. Furthermore, Texas businesses are encouraged by state and federal agencies to adopt these testing protocols to align with wider anti-drug initiatives.
The South Plains, TX government, alongside Lubbock County officials, has been proactive in addressing drug abuse issues through various initiatives. One such program is the collaboration with Texas Health and Human Services to provide educational campaigns about the hazards of drug misuse.
Local efforts include increased funding for rehabilitation centers and partnerships with federal agencies like the Drug Enforcement Administration. These efforts focus on minimizing drug trafficking and supporting addiction recovery through community-based programs.
Recent drug-related events in South Plains, TX, underscore an ongoing effort by law enforcement to tackle drug issues. In early 2023, a major drug bust in Lubbock County resulted in numerous arrests and seizures of multiple narcotics, including methamphetamine and heroin.
These operations are often the result of long-term investigations by local police in coordination with state and federal agencies such as the FBI. During these busts, a strong emphasis is placed on disrupting distribution networks and supporting local prevention initiatives as part of a broader strategy to curb drug abuse.
Accredited Drug Testing offers fast, reliable employment screening services in South Plains, TX. Trusted by employers nationwide for accurate results and exceptional service.
Texas State of Mind
Substance Abuse and Mental Health Services Administration
Recovery Resource Council
Texas o-drug Training Initiative
Texas Health and Human Services
Texas Attorney General
Partnership for Drug-Free Kids
Nar-Anon Family Groups
Texas Criminal Defense Lawyers Association
Texas Department of State Health Services
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Quick, knowledgeable and courteous Janelle worked diligently to support me. I am recommending their services to anyone looking.
Greensboro Joseph - 11/19/2024
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