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Accredited Drug Testing delivers an extensive range of drug and alcohol testing services at our 33 testing locations in and around Tom Bean, Texas. We cater to DOT and non-DOT urine tests, breath alcohol evaluations, EtG tests, and hair follicle analyses for personal, employment, and judicial requirements. Offering rapid results testing and laboratory analysis certified by SAMSA, we provide same-day service with most Tom Bean facilities conveniently located minutes from your residence or workplace. Additional offerings comprise Occupational Health Assessments, Clinical Diagnostics, and Background Verification.
Dial (800) 221-4291 or register online to get started. Simply select your desired test and location—our services are open for personal, employee, or third-party use. Arranging a test is straightforward and swift, available 24/7 through our scheduling team or online portal. Our efficient process ensures setting up drug testing within Tom Bean is hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Tom Bean drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Tom Bean, Grayson County, 15% of high school students reported using illicit drugs in the past year.
Tom Bean, located in Grayson County, experienced a 20% increase in opioid-related ER visits between 2021 and 2022.
Grayson County's Tom Bean reported 8 drug-related arrests per 1,000 residents in 2022.
15% of adults in Tom Bean, Grayson County, reported past year illicit drug use during a 2022 survey.
In 2023, Tom Bean's Grayson County reported 30 drug trafficking cases pending in court.
5% of teenagers in Tom Bean, Grayson County, have been involved in a drug-related offense according to 2022 data.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Tom Bean, TX are proactive in addressing drug use in the workplace through the implementation of drug testing policies. Many businesses require drug testing as a part of their pre-employment screening process and conduct random tests to ensure a safe, drug-free environment.
Adhering to guidelines from the U.S. Department of Labor's Drug-Free Workplace Program, Tom Bean employers strive to educate their workforce on the risks of drug abuse and offer resources for those seeking help. Such measures are instrumental in maintaining workplace safety and productivity.
In partnership with local organizations, employers also provide access to counseling and rehabilitation services, reinforcing their commitment to supporting employees in overcoming addiction challenges.
Tom Bean, TX has been actively engaging in government efforts to mitigate drug abuse issues. The city collaborates with the Texas Department of State Health Services to develop prevention strategies aimed at reducing drug demand. The local Grayson County law enforcement agencies work closely with community organizations to implement educational programs in schools.
Furthermore, Tom Bean benefits from statewide initiatives such as the Governor's Criminal Justice Grants that provide funding for drug prevention activities. Partnership with the federal government through agencies like the Drug Enforcement Administration has enabled Tom Bean to acquire resources necessary for targeted drug enforcement operations.
Tom Bean, TX has witnessed several noteworthy drug-related events in recent years, highlighting the city's ongoing battle against drug abuse. In April 2023, a significant drug bust in Grayson County led to the seizure of large quantities of methamphetamine and heroin, emphasizing the persistent threat posed by drug trafficking.
Local law enforcement agencies work diligently to curb drug activities, often collaborating with state and federal agencies for joint operations. Regular community engagement events, like drug take-back initiatives, aim to educate residents on the dangers of drug abuse and provide safe disposal options for unused medications.
The city's strategic approach in tackling drug issues can be attributed to continuous coordination among law enforcement, community groups, and public health agencies—an effort which enhances community safety and well-being.
Accredited Drug Testing offers fast, reliable employment screening services in Tom Bean, TX. Trusted by employers nationwide for accurate results and exceptional service.
Texas Department of State Health Services
Texas Health and Human Services Commission
Texas Society of Addiction Medicine
HHS o-drug Programs - Texas
DEA Dallas Division
NARCAN
Mental Health TX
Right Step Texas
AA Online Meetings
Grayson County Drug Impact & Prevention
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024