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Accredited Drug Testing provides an extensive array of drug and alcohol testing services at 33 locations in the Big Island, Virginia region. We cater to both DOT and non-DOT testing needs with urine drug screenings, breath alcohol evaluations, EtG alcohol assessments, and hair drug analyses suited for personal, employment, and legal purposes. These services offer rapid results and utilize SAMSA certified labs. Same-day appointments are often available, and most facilities are conveniently located just minutes from your home or workplace. We also offer Occupational Health Testing, Clinical Testing, and Background Checks.
To schedule, call (800) 221-4291 or register online. Select your desired test and nearest site—services are available for personal, employee, or third-party testing. Our hassle-free process ensures scheduling is Fast and Easy, either via our call center or through our online system accessible 24/7. With our efficient method, arranging for drug testing in Big Island is straightforward and convenient.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Big Island drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Big Island, VA, which is part of Bedford County, the opioid prescription rate was reported as 67.3 per 100 people in recent years.
Bedford County reported a 25% increase in drug-related hospital admissions over the last three years, affecting urban areas like Big Island, VA.
The town of Big Island in Bedford County has seen over 50 drug-related arrests annually as per the recent police department reports.
Recent studies have shown that 15% of high school students in Bedford County, including Big Island, have experimented with illicit drugs.
Fentanyl was involved in 40% of the drug overdose cases reported in Big Island, VA, illustrating the county-wide issue with synthetic opioids.
As of last year, Bedford County, where Big Island is located, had a drug overdose death rate of 18 per 100,000 population.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Big Island, VA, are increasingly adopting strict drug testing policies to ensure workplace safety. Many local businesses collaborate with state resources like the Virginia Department of Small Business and Supplier Diversity to establish clear guidelines for drug use and testing.
Pre-employment drug screening has become a common practice. Additionally, many employers in Bedford County participate in programs endorsed by the U.S. Department of Labor, promoting a drug-free workplace environment. Continuous education and awareness on the harms of drug use form part of the onboarding process.
Random drug testing is also being implemented to deter ongoing drug use among employees. This initiative is in line with broader statewide efforts to combat substance abuse, as supported by the Virginia State Government, emphasizing the importance of maintaining healthy and productive work environments.
The government of Big Island, VA, alongside Bedford County, has been proactive in addressing drug problems. They have implemented various preventive campaigns, focusing on education and outreach to reduce drug abuse among youths. Collaborative efforts with agencies like the Virginia Department of Health aim to enhance community awareness and resilience.
Further, the region has seen the establishment of drug courts and rehabilitation programs backed by state funding to support recovery and integration for affected residents. These programs often work in conjunction with the Virginia Department of Medical Assistance Services to provide necessary treatment and support.
In recent years, Big Island, VA, has witnessed several significant drug busts, marking an active stance by the Bedford County law enforcement. These operations often target illegal drug distribution networks and have resulted in the confiscation of substantial quantities of narcotics.
A prominent case involved the seizure of over 500 grams of methamphetamine, disrupting a major supply chain. This operation was conducted in coordination with federal agencies such as the Drug Enforcement Administration to strategically dismantle drug trafficking operations.
The town has also seen community-driven events aimed at reducing drug abuse, such as awareness rallies and prescription drug take-back days, emphasizing public cooperation in addressing these issues. These events are crucial in maintaining open communication lines between residents and law enforcement.
Accredited Drug Testing offers fast, reliable employment screening services in Big Island, VA. Trusted by employers nationwide for accurate results and exceptional service.
Behavioral Health at Virginia Department of Health
Virginia Prevention Works
Virginia Medicaid Addiction and Recovery Treatment Services
Virginia Alcohol Safety Action Program
Outreach Drug and Alcohol Family Counseling Agency
Virginia Network for Victims & Witnesses
Harm Reduction Coalition
Northern Virginia Family Service
Virginia Performs - Drug Misuse Performance Report
Partnership to End Addiction
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024