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At our 31 locations in the Lowes Island, Virginia region, Accredited Drug Testing provides a full range of drug and alcohol testing services. Whether for DOT, non-DOT, individual, employer, or legal purposes, we offer urine drug tests, breath alcohol tests, EtG alcohol screens, and hair drug testing. Enjoy the convenience of rapid result testing and SAMSA certified lab analysis with same-day service options. Most test centers are just minutes away from your office or home. Additional support includes Occupational Health Testing, Clinical Testing, and Background Checks.
Contact us at (800) 221-4291 or register on our website. Choose the specific test and pick a nearby test center—services are available for personal, employee, or third-party testing. Scheduling is swift and straightforward, whether through our call center or online, available 24/7. Our process ensures that arranging drug testing in Lowes Island is both simple and efficient.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Lowes Island drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Lowes Island, Loudoun County, 15% of residents report having used illicit drugs in the past year (2021).
Loudoun County's opioid overdose rate was 12 per 100,000 people in 2022, according to public health data.
A 2020 survey in Lowes Island revealed that 8% of teenagers have experimented with prescription drug misuse.
Loudoun County has seen a 25% increase in drug-related arrests from 2020 to 2022.
In 2021, emergency rooms in Loudoun County treated 500 cases related to substance abuse.
Lowes Island recorded a 22% increase in drug rehabilitation center admissions in 2021.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Lowes Island, VA, have adopted stringent drug testing policies to maintain a safe and productive work environment. Many local companies conduct pre-employment and random drug screenings to deter substance misuse among employees, adhering to guidelines set by the U.S. Department of Labor.
Some businesses collaborate with the Substance Abuse and Mental Health Services Administration to provide employee assistance programs. These initiatives ensure employees receive support for substance use disorders, reflecting a commitment to workforce health and wellbeing.
The government has implemented various initiatives to tackle drug issues in Lowes Island, VA. The Loudoun County Government has partnered with local agencies to enhance education programs on substance misuse and funded rehabilitation centers to aid recovery efforts.
State and federal collaborations aim to address drug-related challenges comprehensively. The Virginia Department of Housing and Community Development supports community programs focusing on prevention and intervention, striving to reduce drug dependency rates in Lowes Island.
In recent months, Lowes Island, VA has witnessed an increased number of drug busts, as local law enforcement intensifies its efforts to combat illegal substance distribution. These operations have led to several arrests and the confiscation of significant quantities of narcotics, showcasing the community's commitment to maintaining a safe environment for its residents.
One notable incident involved the dismantling of a local drug ring operating out of a seemingly innocuous residential area. The operation was carried out in coordination with multiple law enforcement agencies, resulting in the seizure of various illicit drugs and firearms. The successful crackdown was applauded by community leaders who emphasized the importance of vigilance and cooperation in tackling such issues.
Authorities have also reported an increase in drug-related activities in the vicinity of local recreational areas. This has prompted increased surveillance and patrols, aiming to deter potential illegal transactions and ensure public safety. The community has been encouraged to report any suspicious activities, underlining the role of public involvement in addressing drug-related challenges.
Accredited Drug Testing offers fast, reliable employment screening services in Lowes Island, VA. Trusted by employers nationwide for accurate results and exceptional service.
Virginia Alcohol Safety Action Program (VASAP)
Virginia 2-1-1
Alleghany Highlands Community Services
Loudoun County Mental Health, Substance Abuse, and Developmental Services
Prevention Connections
Horizon Behavioral Health
Virginia Department of Behavioral Health and Developmental Services
Sentara Healthcare
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024