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Accredited Drug Testing delivers an array of drug and alcohol testing solutions at our 35 testing sites around Lyndhurst, Virginia. From DOT to non-DOT urine analyses, breath alcohol evaluations, EtG testing, and drug detection in hair, we've got you covered for personal, corporate, and legal reasons. Our Lyndhurst facilities offer quick result testing and SAMSA-accredited lab evaluations, with same-day service possible and many centers conveniently located near your residence or workplace. We also perform Occupational Health Evaluations, Clinical Tests, and conduct Background Checks.
Dial (800) 221-4291 or sign up online. Pick your preferred test and find a convenient location nearby—testing is open to you, your staff, or any individual. Scheduling is swift and straightforward; contact our scheduling team or set up a test anytime online. Our efficient and easy-to-navigate system lets you arrange drug testing close to Lyndhurst with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Lyndhurst drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Lyndhurst, VA experiences a significant number of opioid overdoses annually, with a notable portion occurring in Augusta County.
In 2022, Augusta County reported an increase in methamphetamine-related incidents, affecting communities around Lyndhurst.
Lyndhurst saw an uptick in fentanyl-related arrests in recent years, highlighting a growing issue in Augusta County.
Youth drug use in Lyndhurst has been steadily rising, with Augusta County schools reporting higher than average marijuana usage rates.
Augusta County's drug-related hospital admissions have increased, reflecting Lyndhurst's ongoing struggle with substance abuse.
Local rehabs near Lyndhurst have reported a 25% increase in admissions for heroin addiction in the past two years.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Lyndhurst, VA, acknowledge the impact of drug use on workplace safety and productivity. Many businesses have instituted comprehensive drug testing policies to ensure a drug-free environment. These policies often align with guidelines from the U.S. Department of Labor.
Some firms in Augusta County offer employee assistance programs (EAPs) that include resources and support for substance abuse issues. Companies emphasize the importance of maintaining confidentiality and providing pathways for rehabilitation rather than punishment.
Larger employers might also participate in local drug-free coalitions, aligning with statewide initiatives to combat substance abuse. These partnerships help create a community-focused approach to addressing and managing drug-related incidents in the workplace.
In response to drug abuse challenges, Lyndhurst, VA has been striving to improve community health through various government initiatives. Local authorities have collaborated with state programs like the Virginia Department of Health Professions to monitor and reduce prescription drug abuse. Additionally, federal grants have funded addiction treatment and prevention programs specifically tailored for communities in Augusta County.
Local efforts also include partnerships with organizations such as the U.S. Department of Justice and the Augusta County Sheriff's Office to curb drug trafficking and related crimes. These efforts aim to address not only drug supply issues but also provide educational resources and support networks for individuals struggling with addiction.
Lyndhurst, VA has recently been in the spotlight due to several significant drug busts, leading to increased law enforcement activity in Augusta County. Local police departments, in collaboration with regional task forces, have successfully intercepted large quantities of illicit substances, including methamphetamine and opioids.
Community events have been organized to raise awareness about drug abuse and its effects, drawing attention to the ongoing efforts needed to combat this issue. Programs such as narcan distribution events are frequently held, aiming to save lives through immediate overdose intervention.
Such local initiatives are often supported by county-wide law enforcement campaigns, such as 'Operation Spring Cleaning,' which targets drug dealers and traffickers. These events underscore Lyndhurst's commitment to creating a safer environment for its residents.
Accredited Drug Testing offers fast, reliable employment screening services in Lyndhurst, VA. Trusted by employers nationwide for accurate results and exceptional service.
Virginia Dept of Housing and Community Development
Virginia SBDC
VA Drug and Alcohol Counseling Centers
VCU Health Addiction Treatment
Thriveworks Midlothian Counseling
Blue Heron Wellness
Hannon House
Augusta County Family Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024