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Comprehensive drug and alcohol screening services are available through Accredited Drug Testing at 32 centers around Triangle, Virginia. We administer both DOT and non-DOT urine drug tests, breathalyzers, EtG alcohol tests, and hair follicle testing for individuals and employers, as well as for legal situations. If you are located in Triangle, VA, take advantage of our rapid testing results and certified lab analysis, with same-day service often accessible. Most test locations are nearby, and we also offer Occupational Health, Clinical Testing, and Background Checks.
Reach out by calling (800) 221-4291 or register online. After selecting your desired test, choose a convenient location. Testing is accessible for personal use, employee evaluations, or other purposes. Scheduling is quick and simple, whether via our support team or our 24/7 online system. Our efficient process ensures arranging a drug test near Triangle is straightforward.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Triangle drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Triangle, VA in Prince William County reported a 7% increase in drug-related arrests.
Emergency departments in Prince William County saw 300 opioid-related visits in 2022.
Triangle, VA had an overdose mortality rate of 12.4 per 100,000 in 2021.
In 2021, 15% of high school students in Triangle, VA reported using illegal drugs.
Triangle, VA experienced a 20% increase in drug-related criminal offenses in 2022.
Substance abuse treatment admissions in Prince William County rose by 10% in 2023.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Triangle, VA, are increasingly implementing strict drug testing policies to maintain a drug-free workplace. Many follow guidelines set by the U.S. Department of Labor, which encourages creating a safe and healthy work environment.
In certain industries, routine drug testing is mandatory, ensuring compliance with federal regulations. Employers also provide access to Employee Assistance Programs (EAPs) offering support for those struggling with substance abuse, aligning with policies recommended by the Substance Abuse and Mental Health Services Administration.
In recent years, Triangle, VA, located in Prince William County, has seen an increase in drug-related issues. To combat these challenges, the local government has implemented several initiatives aimed at reducing drug abuse and improving public health. Programs include increased funding for substance abuse treatment and expanded education initiatives in schools. For more resources, visit Prince William County's official site.
Triangle works closely with Virginia's state government to address drug problems. The state offers various services, such as the Virginia Department of Behavioral Health and Developmental Services, which provides support and treatment options. More information can be found on their official website. Additionally, local law enforcement collaborates with federal agencies to target drug trafficking networks.
The town of Triangle, VA has recently been grappling with an uptick in drug-related incidents. Local law enforcement agencies have been working tirelessly to combat the surge. In a recent operation, a joint task force managed to dismantle a significant drug distribution network suspected of trafficking narcotics across multiple neighborhoods in the Triangle area.
In another notable event, authorities conducted a raid on a suspected drug den, which led to the arrest of several individuals and the confiscation of illegal substances. This operation was a result of a months-long investigation that involved undercover work and community tips. The success of this mission has been hailed as a critical step in breaking the cycle of drug distribution in the community.
Furthermore, local schools are also feeling the impact, with several students being caught with narcotics on campus. This has prompted school administrators to initiate a series of educational programs aimed at drug prevention and awareness. These efforts highlight the community’s commitment to addressing the issue at every level, fostering a safer environment for everyone in Triangle.
Accredited Drug Testing offers fast, reliable employment screening services in Triangle, VA. Trusted by employers nationwide for accurate results and exceptional service.
Virginia Department of Health
Virginia Prevention Works
Parent Awareness Coalition
Prince William County Crime Prevention
Community Coalition for Substance Abuse Prevention
Addiction Center of Virginia
Spotsylvania County Substance Abuse Resources
Virginia Alcohol Safety Action Program
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024