Urine| Hair Follicle | Oral Fluid | Blood | ETG
Hair assessment is increasingly recognized as an effective means for identifying drug and alcohol consumption. Hair strands offer a comprehensive history of substance intake by capturing biomarkers within the strands' fibers. Sampling hair near the scalp can provide a detection period of up to nearly three months for various substances. Hair collection is straightforward, challenging to tamper with, and easy to transport.
A 1.5-inch segment of about 200 hair strands (approximately the diameter of a #2 pencil) nearest the scalp yields 100mg, which is ideal for both preliminary testing and confirmation. For extended testing like EtG additions or panels surpassing 10, 150mg is advised. It's best to use a jeweler’s scale for specimen measurement. If scalp hair is not available, an equivalent amount of body hair can be taken. 'Head hair' specifies only scalp hair; 'body hair' includes all other kinds (facial, axillary, etc.).
Process Overview
The primary steps in laboratory drug test processing include Sample Entry, Preliminary Testing, Substance Extraction, and Verification.
Sample Entry pertains to the sample's initial integration into a lab's system. This step ensures the sample's integrity regarding sealing and shipping, assigns a unique LAN (Laboratory Accessioning Number), and concludes any required manual data input absent from an electronic chain of custody record.
Preliminary Testing offers an expedited review for substance presence. Although efficient in negating drug intake across most samples, any positive findings must undergo confirmation for legal acceptance. Samples yielding preliminary positive results necessitate additional verification.
If preliminary results are positive, additional hair is extracted from the original sample for further preparation in the Substance Extraction phase. Drugs are retrieved from hair at a significantly lower concentration than in other methods (e.g., urine or saliva), marking hair analysis as more complex.
Verification of positive preliminary results is managed using GC/MS, GC/MS/MS, or LC/MS/MS techniques. Any presumptive positives undergo a wash process before verification as required. The comprehensive lab procedure from Sample Entry to Verification adheres to the CAP (College of American Pathologists) Hair standard and complies with ISO / IEC 17025 accreditation.
Advantages of hair drug testing:
Limitations:
Note: The term "hair follicle tests" is often a misnomer; the analysis involves the hair strand rather than the underlying follicle.
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