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At our 35 East Palo Alto, CA locations, Accredited Drug Testing delivers extensive drug and alcohol testing services. We cater to individual, business, and legal testing requirements with DOT and non-DOT urine drug tests, breath and EtG alcohol tests, and hair analysis. In East Palo Alto, we facilitate quick result testing and employ SAMSA certified labs. Immediate services are accessible, with most centers conveniently located just moments from your home or workplace. Other offerings include Occupational Health Evaluations, Clinical Screenings, and Background Verification.
To schedule, either dial (800) 221-4291 or register on our website. Simply choose your test and pick a convenient nearby center, available for individuals, staff, or others. Arranging testing is Simple and Swift—connect with our scheduling team or book online around the clock. Our efficient process ensures you can book drug testing near East Palo Alto with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our East Palo Alto drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
East Palo Alto, in San Mateo County, reported a 20% increase in opioid-related deaths from 2019 to 2021.
In San Mateo County, 15% of teens in East Palo Alto admitted to using marijuana in 2020.
East Palo Alto experienced a 30% rise in drug-related arrests between 2018 and 2020.
A 2022 report shows that 25% of emergency room visits in San Mateo County's East Palo Alto involved drug misuse.
In 2023, a survey found that 40% of East Palo Alto residents perceived drug abuse as a major community issue.
San Mateo County's needle exchange program in East Palo Alto served over 500 individuals in 2021.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
In East Palo Alto, CA, many employers adopt strict drug testing policies to ensure a safe and drug-free workplace. Companies may conduct pre-employment, random, or post-accident drug tests. Information on state regulations can be found through the California Department of Industrial Relations.
Some businesses align their policies with federal guidelines, especially those involved in government contracts or transportation. The U.S. Department of Labor's Drug-Free Workplace Program offers guidance to help employers maintain compliance and create effective policies.
Government initiatives in East Palo Alto, CA, under San Mateo County include collaborative efforts with San Mateo County Behavioral Health and Recovery Services. These programs focus on prevention, treatment, and recovery for those impacted by substance misuse.
San Mateo County's public health department supports East Palo Alto through funding and partnerships with local organizations to combat drug problems. State-level efforts by California Department of Health Care Services also provide critical resources and guidelines for substance abuse treatment in the community.
East Palo Alto, CA has been experiencing significant challenges related to drug trafficking and use. Recent local law enforcement efforts have led to several high-profile drug busts. These operations have focused primarily on curbing the distribution of illicit substances in the community, aiming to dismantle the networks responsible for the production and sale of drugs that contribute to crime and addiction in the area.
Authorities in East Palo Alto have collaborated with regional and federal agencies to address the complex issue of drug-related crime. Through coordinated efforts, law enforcement has succeeded in apprehending key figures involved in narcotics operations. These busts often lead to the seizure of substantial quantities of drugs, firearms, and money, highlighting the scale of illegal activity present in the region.
Community outreach programs have been integral in assisting East Palo Alto residents affected by drug use and related crimes. These initiatives aim to provide education on drug prevention and offer rehabilitation opportunities for those seeking to escape the cycle of addiction. By fostering community resilience and collaboration, local organizations hope to minimize the impact of drug-related issues in the area.
Accredited Drug Testing offers fast, reliable employment screening services in East Palo Alto, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
Drug Free Northern California
Partnership for Safe and Healthy Communities
Harm Reduction Coalition - California
San Mateo County Behavioral Health
California Healthline
SAMHSA National Helpline
NAMI HelpLine
Related Care Network
California Addiction Recovery Resources
Counseling California
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024