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Accredited Drug Testing provides extensive screening services for drugs and alcohol at our 30 testing sites in the Los Altos Hills, California area. We conduct DOT and non-DOT urine tests, breath alcohol screenings, EtG alcohol analysis, and hair drug tests for personal, corporate, and legal purposes. Rapid results tests and SAMSA-certified lab analyses are offered, with same-day service accessible. Most Los Altos Hills testing centers are conveniently located near your home or workplace. We also offer Occupational Health Exams, Clinical Testing, and Background Screening.
To schedule a test, call (800) 221-4291 or register online. Pick your desired test and find a nearby center—testing options are available for you, staff, or others. Our process makes scheduling swift and simple, with a dedicated scheduling team ready by phone or online anytime. With our efficient system, arranging a local drug test in Los Altos Hills is straightforward.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Los Altos Hills drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Santa Clara County, 5% of adults have engaged in illicit drug use in the past year.
Los Altos Hills has seen a 20% decrease in drug-related arrests over the past three years.
Santa Clara County reported 30 opioid-related deaths last year.
High school surveys show a 15% rate of marijuana use among students in Santa Clara County.
Emergency rooms in Santa Clara County reported over 200 opioid overdose cases in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Los Altos Hills, CA, adopt drug testing policies that align with California state regulations, ensuring a drug-free workplace. Many companies require pre-employment drug screening and adhere to guidelines set forth by the California Department of Industrial Relations (dir.ca.gov).
In addition to pre-employment tests, random testing is employed by some organizations, particularly in industries where safety is prioritized. This approach helps maintain compliance with federal regulations outlined by the U.S. Department of Labor (dol.gov).
In Los Altos Hills, CA, government efforts to combat drug abuse involve coordination at both local and county levels. The Santa Clara County Public Health Department (sccgov.org) leads initiatives focusing on education and prevention.
State programs such as those managed by the California Department of Health Care Services (dhcs.ca.gov) provide support to local efforts, including funding for community-based interventions.
In recent months, Los Altos Hills has seen a significant increase in drug busts, with local authorities intensifying their efforts to combat drug trafficking. The Sheriff's Department has reported multiple incidents involving the seizure of large quantities of illegal substances, including methamphetamine and cocaine, which were destined for distribution throughout Santa Clara County.
One of the most notable drug-related events in Los Altos Hills involved the arrest of several individuals suspected of operating a sophisticated drug manufacturing operation. The operation was set up in a secluded area, making it difficult for the police to trace its origins. This bust has highlighted the need for increased vigilance and community involvement in reporting suspicious activities.
The Los Altos Hills community has responded proactively to these events by participating in educational programs aimed at raising awareness about drug abuse and its consequences. Local schools have initiated campaigns to educate students and parents about the dangers of drug use, working in collaboration with law enforcement to ensure a safer environment for everyone.
Authorities have urged residents to be on the lookout for signs of drug activity and to report any suspicious behavior to the local police. This collaborative approach aims to strengthen community bonds and ensure that Los Altos Hills remains a safe and drug-free area for its residents, highlighting the critical role that community vigilance plays in preventing drug-related incidents.
Accredited Drug Testing offers fast, reliable employment screening services in Los Altos Hills, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
SAMHSA's National Helpline
National Institute on Drug Abuse
Santa Clara County Behavioral Health
Department of Drug and Alcohol Programs
California Healthline
California Addiction Recovery
Counseling California
Recovery.org
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024