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At Accredited Drug Testing, we offer an extensive range of drug and alcohol testing services at our 38 locations around El Segundo, California. Our offerings include DOT and non-DOT urine analyses, breath alcohol evaluations, EtG testing for alcohol, and hair follicle drug tests, tailored for personal, corporate, or legal requirements. Quick testing with results reported rapidly and certified by SAMSA laboratories is available on the same day, with most El Segundo facilities situated conveniently close to your residence or workplace. Additional offerings cover Occupational Health Screening, Clinical Testing, and Background Verification.
To schedule a test, dial (800) 221-4291 or register via our website. Choose the test you require and select a testing center nearby—available for personal use, employee screening, or third-party individuals. Our process is quick and simple; you can contact our scheduling team or set up your test online at any time. Arranging drug tests near El Segundo has never been more direct and hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our El Segundo drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
El Segundo, located in Los Angeles County, reported a 15% rise in drug-related arrests from 2018 to 2021.
In 2020, El Segundo's high school reported a 10% increase in drug-related incidents compared to five years ago.
Los Angeles County, including El Segundo, witnessed a 25% increase in opioid-related deaths between 2019 and 2021.
The El Segundo Police Department noted a 20% increase in methamphetamine seizures from 2017 to 2020.
A 2021 survey by Los Angeles County showed that 8% of adults in El Segundo had misused prescription drugs in the past year.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in El Segundo, CA are increasingly adopting stringent drug testing policies to ensure a safe and productive work environment. Many companies utilize resources from the California Department of Industrial Relations to structure their policies around legal guidelines and employee rights.
Some businesses, particularly in sectors like aerospace and manufacturing, require pre-employment drug screenings and periodic tests for their employees. These policies are often guided by federal standards such as those set by the U.S. Department of Labor to comply with industry-specific regulations and maintain safety standards.
The government of El Segundo, CA has focused significant resources on combating drug abuse by implementing community programs and support networks. Collaborative efforts with the Los Angeles Homeless Services Authority play a crucial role in addressing substance abuse among homeless populations.
State initiatives, such as those outlined by the California Department of Health Care Services, provide frameworks and funding to support local prevention efforts in El Segundo. These initiatives aim to improve treatment accessibility and educate residents on the dangers of drug misuse.
In a recent joint operation, El Segundo law enforcement coordinated with federal agencies leading to a major drug bust. The operation uncovered approximately 100 pounds of cocaine concealed within shipment containers. Officers reported that the meticulous planning and intelligence-gathering were key factors that ensured the successful dismantling of the trafficking ring operating in the region.
El Segundo Police recently arrested several individuals believed to be involved in the distribution of methamphetamine across the city. Officers executed multiple search warrants leading to the seizure of drugs valued over $200,000. This operation highlights the collaborative efforts of local law enforcement to combat the rise of illegal substance distribution and enhance community safety.
A drug-related incident in downtown El Segundo resulted in chaos as police chased suspects following a tip-off about an illegal drug transaction. The pursuit concluded without casualties but successfully resulted in the capture of several key figures suspected of managing local distribution networks. This event has prompted city officials to increase surveillance measures in known hotspots.
Following an anonymous tip-off, El Segundo narcotics teams raided an abandoned warehouse, discovering a small-scale lab manufacturing synthetic drugs. The operation was believed to be run by a local gang aiming to capitalize on the city's demand. Law enforcement officers expressed relief at shutting down the dangerous operation and highlighted the importance of community cooperation in such investigations.
Accredited Drug Testing offers fast, reliable employment screening services in El Segundo, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
California Department of Health Care Services
Los Angeles Homeless Services Authority
Los Angeles County Website
Drug Free New Hampshire
National Council on Alcoholism and Drug Dependence
Addiction Center
Los Angeles County Resource Locator
Find Treatment.gov
Substance Abuse and Mental Health Services Administration
Recovery.org California Directory
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This is by far the easiest way to get my lab work ordered and paid for. The phone calls are short and to the point. They don’t try to push extra sales on you and when I walk in to the clinic I simply show my donor pass and with in a matter of minutes I’m done. I will continue to use ADT in the future.
Jason Jackson - 7/19/2025
Everything was great, the staff was very polite. Thank you.
Olga Petrova - 9/19/2024
The visit here is always the best . The place is always really clean. The employees are super courteous, very polite, and professional. This is the only drug lab I like to go do my drug and alcohol test. I would like to tell them thank you so much for thier excellent performance and job
Eli Gonzalez - 1/4/2025