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Accredited Drug Testing delivers a full suite of drug and alcohol screening solutions through our 36 testing facilities around Manhattan Beach, CA. We cater to both DOT and non-DOT urine drug screenings, alongside breath alcohol tests, EtG alcohol checks, and hair drug assessments. Our offerings are designed to accommodate individuals, corporate employers, and legal cases. Rapid outcomes for tests in Manhattan Beach are provided, supported by SAMSA certified labs, with immediate service options. Most sites are conveniently situated near homes or workspaces. We extend our services to include Occupational and Clinical Health Testing, as well as Background Checks.
Dial (800) 221-4291 or register via our site. Select your test category and choose a nearby facility—ideal for personal, employee, or third-party testing. Scheduling is straightforward and efficient; contact our booking line or schedule online round-the-clock. Our integrated process ensures that organizing a drug test near Manhattan Beach is exceptionally simple.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Manhattan Beach drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Manhattan Beach, Los Angeles County reported a 7% increase in drug overdose deaths in 2022.
In 2022, 15% of high school students in Manhattan Beach, Los Angeles County reported using marijuana.
The city of Manhattan Beach, Los Angeles County saw a 10% rise in prescription drug misuse cases in 2022.
Los Angeles County data indicates that Manhattan Beach had a 5% increase in drug-related arrests in 2022.
In 2022, treatment centers in Manhattan Beach, Los Angeles County experienced a 20% rise in opioid addiction cases.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Manhattan Beach, CA, are increasingly adopting drug testing policies to maintain workplace safety and productivity. Many companies conduct pre-employment screening, as well as random testing, to deter substance misuse. This is in line with state guidelines from the California Department of Industrial Relations.
Organizations are also encouraged to raise awareness through educational programs and workplace seminars. These initiatives, supported by national resources like SAMHSA, aim to inform employees about the dangers of drug use and encourage support for affected individuals in the workplace environment.
Moreover, businesses collaborate with external drug testing services that follow strict standards for accuracy and confidentiality. These partnerships ensure that testing is conducted ethically, respecting employee rights while prioritizing health and safety.
The government of Manhattan Beach, CA, is actively addressing drug problems through various initiatives. The city collaborates with local government agencies to strengthen community programs aimed at prevention and education. Moreover, state-level support from California Department of Health Care Services aids in providing treatment and prevention resources.
Law enforcement plays a critical role by increasing patrols and implementing drug take-back programs. These efforts are supported by partnerships with federal entities like the Drug Enforcement Administration to curb the distribution of illicit substances and enhance public safety in Los Angeles County.
In recent months, Manhattan Beach has seen a notable increase in drug-related incidents, prompting a stronger response from local law enforcement. Officers have been vigilant in monitoring suspicious activities around known hotspots and conducting targeted operations to curb the flow of illegal substances. Community members are encouraged to report any suspicious activities, playing an active role in keeping their neighborhoods safe.
A significant drug bust in Manhattan Beach led to the seizure of various controlled substances, including fentanyl and methamphetamines, along with several thousand dollars in cash. This operation was part of a coordinated effort by local police and federal agencies. Authorities emphasize the importance of community cooperation in identifying and dismantling drug networks that pose a threat to public safety.
Manhattan Beach residents recently participated in a drug take-back event, allowing them to safely dispose of unused prescription medications. This initiative, sponsored by the local police department, aims to reduce the risk of prescription drug abuse and accidental poisoning. Community involvement in such events underscores the collective effort to combat drug misuse and its harmful impacts.
Recent undercover operations in Manhattan Beach have revealed alarming trends in the distribution of counterfeit pills laced with dangerous substances. Local authorities are prioritizing educational outreach to inform the public about the risks of such counterfeit drugs. Ongoing investigations aim to identify and dismantle the sources of these hazardous substances infiltrating the community.
Local schools in Manhattan Beach have ramped up educational programs focused on drug prevention and awareness. These programs, often held in collaboration with law enforcement officers, aim to equip students with the knowledge and skills necessary to resist peer pressure and avoid substance abuse. The community's proactive stance is vital in fostering a safer, drug-free environment for future generations.
Accredited Drug Testing offers fast, reliable employment screening services in Manhattan Beach, CA. Trusted by employers nationwide for accurate results and exceptional service.
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Partnership to End Addiction
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Tarzana Treatment Centers
Matrix Institute on Addictions
CA SBIRT
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024