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Accredited Drug Testing delivers a full suite of drug and alcohol testing at 31 locations around Lomita, California. Our services include DOT-compliant and non-DOT urine drug screenings, breath alcohol analysis, EtG alcohol detection, and hair drug tests designed for individuals, employers, or legal requirements. In Lomita, CA, we offer quick testing results and SAMSA certified lab evaluations with same-day availability. Most centers are conveniently situated near your home or office. Additional offerings encompass Occupational Health Testing, Clinical Testing, and Background Screenings.
Dial (800) 221-4291 or register online to select your desired test and choose a nearby center. Testing is intended for self, employees, or other individuals. Arranging a test is quick and straightforward; contact our scheduling team or book online at any time. Our efficient, user-friendly platform makes organizing local drug testing in Lomita simple and hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Lomita drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Lomita, CA saw a 15% increase in opioid-related incidents in 2022, according to Los Angeles County reports.
In Los Angeles County, where Lomita is located, drug overdoses accounted for over 500 deaths in 2022.
A 2022 survey showed that 12% of high school students in Lomita, CA reported using illicit drugs in the past month.
Fentanyl-related deaths in Los Angeles County, including Lomita, doubled between 2020 and 2021.
Lomita recorded over 200 drug-related hospital visits in 2021, says the California Department of Public Health.
Methamphetamine usage was responsible for 30% of the drug-related arrests in Lomita, CA in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Lomita, CA, have stringent drug testing policies to ensure a safe and productive work environment. Many businesses utilize pre-employment drug screenings and regular checks to adhere to legal standards and maintain operational integrity. For industry regulations, employers often refer to guidelines provided by the U.S. Department of Labor.
Local companies in industries such as transportation and healthcare have specific drug policies aligned with state laws to prevent substance misuse among employees. These policies often include random drug testing and compliance with the California Department of Fair Employment and Housing's statutes for workplace safety.
The government of Lomita, CA, in collaboration with Los Angeles County, has implemented a variety of initiatives to combat drug abuse. These include preventive programs, education, and community outreach initiatives designed to reduce drug use and support affected individuals. Los Angeles County Department of Health Services provides resources and support for addiction treatment and prevention.
Additionally, state-level partnerships with agencies like the Substance Abuse and Mental Health Services Administration (SAMHSA) offer federal support and resources for local communities, including Lomita. The focus is on expanding access to treatment and coordinating local efforts to build a comprehensive approach to preventing and treating substance abuse.
In recent years, Lomita, CA, has witnessed a range of drug-related incidents, shaking the normally peaceful community. Local law enforcement has increased efforts to curb illegal drug activities, leading to several successful busts. These operations often involve coordination with larger drug task forces to dismantle distribution networks affecting the area. The crackdown is part of ongoing initiatives to ensure community safety and well-being.
Residents of Lomita have become more vigilant in reporting suspicious activities, greatly assisting police efforts to disrupt drug trafficking. Recently, a significant bust on Narbonne Avenue resulted in the seizure of various substances, highlighting the community’s proactive role. This increased cooperation between locals and law enforcement has led to several arrests, illustrating the effectiveness of community policing strategies.
Educational programs highlighting the dangers of drug abuse have become a focal point in Lomita’s efforts to prevent youth involvement with drugs. Local schools often collaborate with law enforcement to provide workshops and seminars for students, helping to raise awareness about the risks associated with drug use. By fostering an informed youth, Lomita aims to reduce future drug-related incidents significantly.
Despite these efforts, challenges remain as new synthetic drugs make their way into Lomita. Law enforcement continues to adapt by staying ahead of drug trends and utilizing advanced technology in their operations. Continued community engagement and innovation in policing strategies are crucial in tackling the evolving nature of drug-related crimes in the area, ensuring a safer environment for all residents.
Accredited Drug Testing offers fast, reliable employment screening services in Lomita, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
California Health & Safety Programs
Los Angeles County Department of Public Health
Drug Policy Alliance
Alcoholics Anonymous
Nar-Anon Family Groups
Recovery.org
SMART Recovery
California Healthline
SAMHSA Treatment Services Locator
CDC - California Drug Overdose
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024