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Accredited Drug Testing delivers a wide array of drug and alcohol testing solutions at our 31 sites around Rancho Palos Verdes, California. We conduct both DOT and non-DOT urine screenings, breath alcohol assessments, EtG alcohol evaluations, and hair analysis for personal, corporate, and legal purposes. Quick results and SAMSA-approved lab analysis are offered, and same-day services can be arranged at most of the Rancho Palos Verdes facilities, conveniently close to your home or workplace. Our services also extend to Occupational Health, Clinical Testing, and Background Verification.
Connect by calling (800) 221-4291 or register through our website. Choose your desired test and the nearest center—ideal for personal, employee, or third-party testing. Setting up a test is quick and straightforward, contact our team or book online anytime. The seamless process ensures that coordinating a drug test in Rancho Palos Verdes is remarkably easy.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Rancho Palos Verdes drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Rancho Palos Verdes, located in Los Angeles County, experienced a 25% increase in opioid-related incidents in 2021.
In 2022, Rancho Palos Verdes had a reported 12% rate of substance abuse among youth aged 12-17 in Los Angeles County.
Approximately 70% of drug users in Rancho Palos Verdes identify as using marijuana, according to a 2022 survey.
Rancho Palos Verdes saw a slight decline in methamphetamine use by 5% in Los Angeles County in 2023.
Los Angeles County, including Rancho Palos Verdes, reported around 1,200 drug overdose deaths in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Rancho Palos Verdes are required to adhere to state and federal guidelines regarding drug testing policies. Many local businesses conduct pre-employment drug testing and random screenings, aligning with the policies outlined by the U.S. Department of Labor.
These employers often provide Employee Assistance Programs (EAPs) to support employees dealing with substance use issues, ensuring a drug-free workplace and promoting well-being among staff.
The government of Rancho Palos Verdes, alongside Los Angeles County, has implemented various programs to combat drug abuse. These include education programs in schools and community outreach events to raise awareness and provide resources for those affected by substance abuse.
State-level initiatives like California's Department of Health Care Services provide additional support through treatment services and policy planning.
Rancho Palos Verdes, a coastal city known for its picturesque landscapes, has recently seen a rise in local drug-related events. Law enforcement agencies have intensified their efforts to combat the proliferation of illegal substances, resulting in multiple drug busts throughout the area. These operations aim to dismantle drug networks and protect the community from the adverse effects of narcotics and associated criminal activities.
Community involvement plays a crucial role in addressing drug-related issues in Rancho Palos Verdes. Residents are encouraged to report suspicious activities, which assists law enforcement in identifying and targeting potential drug operations. Public forums and community meetings are frequently held to raise awareness and educate citizens on the dangers and signs of drug abuse, fostering a collaborative environment to ensure safety.
The proactive stance taken by Rancho Palos Verdes authorities has shown promising results, with several high-profile arrests made in recent months. Collaborations with neighboring cities and federal agencies have strengthened the crackdown on drug traffickers. This multi-agency approach not only disrupts illegal drug trade but also helps in rehabilitating affected individuals, steering them towards recovery and reintegration into society.
The impact of drug-related events is felt across the city, affecting families and community morale. Prevention programs, especially targeting youth, are increasingly emphasized in local schools. Educators and law enforcement officers work together to present engaging workshops about the risks of drug use, aiming to equip students with knowledge and resilience against peer pressure and drug influence.
Despite the challenges posed by drug-related incidents, Rancho Palos Verdes remains committed to creating a safer environment for its citizens. Efforts to enhance local policing, combined with community support and education, are crucial in addressing the root causes of drug abuse. By nurturing an informed and vigilant community, the city aims to sustain its reputation as a vibrant and secure residential area.
Accredited Drug Testing offers fast, reliable employment screening services in Rancho Palos Verdes, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
California Department of Health Care Services
California Substance Abuse Resource Network
Substance Abuse and Mental Health Services Administration
LA County Substance Abuse Prevention and Control
Awakenings Outpatient Services, CA
Tarzana Treatment Centers
Peninsula Center for Health Care Services, RPV
National Center for Drug Abuse Statistics
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024