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Accredited Drug Testing delivers a full spectrum of drug and alcohol testing services across our 30 testing locations in the Manhattan, Kansas area. We facilitate both DOT and non-DOT urine drug screenings, breath alcohol assessments, EtG alcohol screenings, as well as hair follicle drug tests for individuals, businesses, and legal purposes. In Manhattan, KS, we provide quick result testing and SAMSA certified lab analysis, with same-day availability, ensuring most locations are just minutes from your home or workplace. Additional offerings include Occupational Health Assessments, Clinical Examinations, and Background Verifications.
Reach out at (800) 221-4291 or sign up online. Choose your specific test and pick a convenient location—testing is accessible for personal use, employees, or others. Booking is Fast and Easy, connect with our scheduling team or book your test online, 24/7. Our efficient and intuitive process ensures you can set up drug testing near Manhattan seamlessly.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Manhattan drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Manhattan, Riley County, opioid overdoses increased by 15% between 2020 and 2021.
Riley County reported a 25% higher rate of methamphetamine-related arrests in 2022.
In 2023, 10% of high school students in Manhattan, KS admitted to recreational drug use.
Manhattan, Riley County, saw a 5% increase in alcohol-related hospital visits from 2021 to 2022.
Riley County's drug court program expanded by 20% to manage increasing cases of drug offenses.
Prescription drug abuse in Riley County increased by 9% in 2022, affecting local healthcare resources.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Several employers in Manhattan, KS, have adopted rigorous drug testing policies to maintain a safe and productive work environment. These policies often include pre-employment screenings, random drug tests, and post-accident testing to deter substance abuse among employees.
Local businesses align their drug testing policies with the guidelines provided by the Kansas Department of Labor. The agency offers resources and support for employers seeking to implement comprehensive drug prevention measures. For more information, visit the Kansas Department of Labor website.
In response to rising drug-related issues, the government has implemented several initiatives in Manhattan, KS. Riley County collaborates with state programs to enhance drug education in schools. These programs aim to prevent drug abuse and support prevention efforts in the community.
The Kansas Department for Aging and Disability Services works closely with local agencies to provide rehabilitation and counseling services. By emphasizing treatment over incarceration, the government aims to reduce drug-related crimes. For more information, visit the KDADS official website.
In recent months, local law enforcement agencies in Manhattan, KS have increased their efforts to curb drug trafficking in the area. Leveraging community tips and strategic surveillance, authorities have successfully executed several drug busts targeting known distribution networks. These initiatives not only remove harmful substances from the streets but also aim to disrupt the operations of larger criminal organizations involved in narcotics.
Collaborative efforts between the Riley County Police Department and Kansas State University have been crucial in identifying hotspots for drug activity. By focusing on areas with high foot traffic, such as Aggieville, officers have managed to apprehend several individuals involved in selling illegal substances. These operations emphasize the importance of community engagement in combatting illicit drug activity in Manhattan.
The impact of drug-related crimes in Manhattan reaches beyond immediate safety concerns, affecting local businesses and neighborhoods. To address these issues, community outreach programs have been introduced to educate residents about the dangers of drug abuse. Workshops and informational sessions are designed to empower citizens with knowledge, thereby creating a network of vigilance against drug-related incidents.
Technological advancements in surveillance have played a role in recent drug bust successes in Manhattan. The integration of real-time monitoring systems and data analysis tools allows law enforcement to predict potential operations and gather necessary evidence. This technological edge has improved response times and refined strategies, making law enforcement efforts more efficient and effective in tackling drug crimes.
Despite progress in combating drug-related issues, challenges remain in addressing the root causes of substance abuse in Manhattan. Local organizations are increasingly focused on providing support resources for individuals struggling with addiction. By fostering partnerships with rehabilitation centers and mental health services, the community is striving to provide alternatives to the cycle of substance abuse, ultimately aiming for long-term positive change.
Accredited Drug Testing offers fast, reliable employment screening services in Manhattan, KS. Trusted by employers nationwide for accurate results and exceptional service.
Riley County Community Corrections
Labette Center for Mental Health Services
Valley Hope of Moundridge
Healing with Care Services
DCCCA, Inc.
Mirror, Inc.
Kansas Alliance for Drug Endangered Children
Kansas Department for Aging and Disability Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024