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Accredited Drug Testing delivers a full range of drug and alcohol screening options at our 33 testing facilities around Haledon, New Jersey. We cater to DOT and non-DOT urine, breath alcohol, EtG alcohol, and hair drug tests for private, corporate, and legal purposes. With quick results and analysis by SAMSA certified labs, we offer same-day service where many testing sites in Haledon are conveniently located. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Dial (800) 221-4291 or register on our website. Pick your preferred test and find a location close to you—testing services are accessible for personal, employee, or third-party needs. Scheduling is Efficient and Convenient; connect with our customer service or book online anytime. Our efficient and simple procedure makes it easy to arrange drug testing in Haledon with minimal effort.
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At our Haledon drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Haledon, NJ located in Passaic County, there was a 15% increase in drug-related arrests over the past year.
Passaic County reported a 5% rise in opioid overdoses, a concern for Haledon, NJ.
Among teens in Haledon, 12% admitted to trying illicit drugs within the last year.
A survey indicated that 8% of adults in Haledon, NJ use prescription medications non-medically.
In Passaic County, including Haledon, 20% of drug rehab admissions are for heroin.
Haledon, NJ shows a decline in drug-related deaths, with a 2% decrease reported in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
In Haledon, NJ, employers are increasingly prioritizing drug testing policies to ensure a safe and productive work environment. Many local businesses conduct pre-employment drug screenings and random drug tests for existing employees. These measures are in line with state regulations, ensuring compliance with the
Companies understand the importance of maintaining a drug-free workplace, not only for the safety of their employees but also for the overall productivity of their operations. Some employers provide access to employee assistance programs that offer support and counseling for those dealing with substance abuse, reinforcing their commitment to employee well-being.
The emphasis on drug-testing policies reflects a broader effort by businesses in Haledon to align with the public health objectives of reducing drug dependence and promoting a healthy community. This proactive approach serves as a deterrent against drug misuse and encourages a more responsible workforce.
The government in Haledon, NJ, in collaboration with Passaic County, has been proactive in combating drug abuse through a series of initiatives. These include the implementation of educational programs in schools, aimed at preventing drug use among youths. Local authorities have also increased funding for local rehabilitation centers to offer better support and resources for those struggling with addiction.
State and federal agencies have supported these efforts as well. Programs like the NJ Department of Human Services provide guidelines and resources to tackle drug-related issues. Additionally, the government supports various community initiatives to raise awareness and provide direct assistance, thereby creating a supportive environment for recovery.
In recent periods, Haledon, NJ, has seen a number of significant drug busts targeting local narcotics networks. Law enforcement agencies have been actively involved in dismantling operations that distribute illegal substances in the area. Efforts have been intensified, focusing on curbing the distribution of opioids and other controlled drugs, which have been identified as a growing concern by local authorities.
As part of a coordinated effort, Haledon police have collaborated with neighboring municipalities and state agencies. Their goal is to pool resources and share intelligence to effectively tackle drug trafficking. This partnership has resulted in numerous raids and seizures, disrupting the supply chains that feed the local market and aiming to restore safety and security to the community.
Community initiatives have also played a pivotal role in addressing the drug problem in Haledon. Town meetings and outreach programs emphasize the importance of preventing drug abuse and educating residents about the risks associated with substance addiction. These programs aim to foster a collaborative environment where citizens and authorities can work together to combat drug issues.
Accredited Drug Testing offers fast, reliable employment screening services in Haledon, NJ. Trusted by employers nationwide for accurate results and exceptional service.
New Jersey DOT/Non DOT Physicals
NJ Department of Human Services
NJ n-drug Access
NJ State Police n-drug Fact Sheet
NJ Natural Gas Drug Abuse Resources
Passaic County Mental Health and Addiction Services
Haledon Drug Education Program
Recovery Centers of America, NJ
SAMHSA
ATLAS
211 Substance Abuse Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024