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Accredited Drug Testing provides a wide range of drug and alcohol testing services at 30 centers in the Saint Stephens, North Carolina area. Our offerings include DOT and non-DOT urine drug tests, breath alcohol screens, EtG alcohol assessments, and hair follicle drug testing tailored for personal, corporate, and legal purposes. Saint Stephens, NC, residents benefit from quick turnarounds with SAMSA-certified lab analyses and same-day appointments available; most testing centers are conveniently located near homes or workplaces. Additional offerings encompass Occupational Health Testing, Clinical Testing, and Background Verifications.
Dial (800) 221-4291 or register online. Just select a test and a convenient nearby center—our tests cater to individuals or businesses. Organizing a test is simple and fast; contact our scheduling team or set up your appointment online any time, day or night. Our efficient, user-friendly system ensures easy drug testing in Saint Stephens.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Saint Stephens drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, drug-related arrests in Saint Stephens, located in Catawba County, accounted for over 15% of the county's total arrests.
Saint Stephens, NC saw a 10% increase in opioid overdose deaths in 2021 compared to the previous year.
Catawba County reported that 18% of high school students in Saint Stephens admitted to trying illicit drugs in 2021.
In 2020, emergency room visits for drug overdoses in Saint Stephens, Catawba County, rose by 25%.
A Catawba County health report from 2021 indicated that 23% of drug-related hospitalizations in the county were from Saint Stephens.
Law enforcement agencies in Catawba County noted a 30% increase in drug trafficking cases in the Saint Stephens area in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Saint Stephens, NC, are increasingly adopting stringent drug testing policies to ensure workplace safety and productivity. These policies often include pre-employment testing and random drug tests to deter substance abuse among employees. Companies like Commscope have comprehensive drug policies in place.
The Catawba County Chamber of Commerce collaborates with local businesses to provide resources for implementing effective drug testing programs. This approach not only enhances workplace safety but also supports community-wide efforts against substance abuse. Catawba County Chamber of Commerce.
The local government in Saint Stephens, NC, is actively working to address the drug problem affecting Catawba County. Collaborative efforts with organizations like the North Carolina Department of Health and Human Services aim to reduce substance abuse through public awareness campaigns and treatment programs. North Carolina Department of Health and Human Services.
Partnerships with federal agencies like the DEA also help in combating drug trafficking. Programs focusing on prevention and rehabilitation are being implemented to tackle the root causes of drug addiction and support recovery, ensuring a safer community environment.
In recent years, Saint Stephens, NC, has seen significant law enforcement efforts to tackle drug-related activities. Catawba County Sheriff's Office conducted a major drug bust in 2023, leading to the seizure of large quantities of methamphetamine and the arrest of multiple suspects involved in a regional drug ring.
Local authorities regularly organize drug take-back events to combat prescription drug abuse, allowing residents to safely dispose of unused medications. These events have seen positive community engagement, contributing to reducing the availability of drugs on the streets.
Community-driven initiatives in Saint Stephens are crucial in addressing the drug issues. Town hall meetings and forums are held to educate the public and discuss strategies for tackling drug abuse, with participation from both residents and local officials.
Accredited Drug Testing offers fast, reliable employment screening services in Saint Stephens, NC. Trusted by employers nationwide for accurate results and exceptional service.
North Carolina DOT/Non DOT Physicals
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North Carolina Department of Insurance
North Carolina General Assembly
NC Department of Public Safety
North Carolina Alliance for Behavioral Healthcare
North Carolina Justice Center
North Carolina Association of Pharmacists
North Carolina Medical Society
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024