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Accredited Drug Testing provides a broad range of drug and alcohol testing solutions at 40 locations in the Jacksonville, Pennsylvania vicinity. Our services cover DOT and non-DOT urine analyses, breath alcohol assessments, EtG tests for alcohol, and hair drug examinations tailored for personal, workplace, or legal purposes. Rapid test results and SAMSA certified lab assessments are offered, with same day options in Jacksonville, PA, conveniently situated near homes and workplaces. We also offer services like Occupational Health Evaluations, Clinical Testing, and Background Verifications.
Dial (800) 221-4291 or sign up online. Easily pick your desired test and a convenient location—tests are suitable for you, your staff, or someone else. Arranging for testing is Quick and Simple: reach out to our scheduling team or book online anytime. Our efficient and easy-to-navigate system simplifies setting up a drug test in Jacksonville.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Jacksonville drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Jacksonville, PA, located in Centre County, a 2018 report indicated that opioid-related overdose deaths accounted for 70% of all drug fatalities in the area.
Centre County, which encompasses Jacksonville, saw a 36% rise in heroin-related incidents from 2016 to 2019.
A 2019 survey found that 15% of high school students in Jacksonville, PA, admitted to trying illicit drugs at least once.
In 2020, Jacksonville's emergency services responded to a 28% increase in drug overdose calls compared to the previous year.
Prescription drug misuse was responsible for 40% of substance abuse treatment admissions in Centre County in 2019.
The local police department in Jacksonville, PA, reported a threefold increase in drug-related arrests from 2017 to 2020.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Jacksonville, PA, have taken proactive stances on drug policies, often requiring pre-employment drug tests. Many businesses collaborate with local agencies like Center for Workplace Health to develop effective testing strategies.
Companies understand the importance of maintaining a drug-free workplace, not only for safety but also for increasing productivity. As part of these efforts, ongoing random testing may be implemented, supplemented by support for employees seeking help through SAMHSA programs.
The government has intensified efforts in Jacksonville, PA to tackle drug issues with initiatives focusing on prevention and treatment. Programs like Targeting DMHSAS work within Centre County to address substance abuse through education and support mechanisms.
Recent collaborative measures involve Centre County officials actively working with state agencies such as the Pennsylvania Opioid Abuse Task Force to address the opioid crisis through comprehensive strategies that include law enforcement, healthcare provider training, and community outreach.
Recent major drug busts in Jacksonville, PA, such as the 2022 operation involving local law enforcement and DEA agents, highlight ongoing efforts to combat trafficking. Reports from the DEA described seizure operations as crucial in dismantling drug distribution networks.
Community events aimed at drug awareness, such as the Jacksonville Drug Awareness Week, have seen increasing participation. These events facilitate dialogue between citizens, law enforcement, and health professionals, proving crucial in educating the public about the dangers of drug use.
Accredited Drug Testing offers fast, reliable employment screening services in Jacksonville, PA. Trusted by employers nationwide for accurate results and exceptional service.
Pennsylvania DOT/Non DOT Physicals
Pennsylvania Department of Drug and Alcohol Programs
PA o-drug Epidemic Guide
Center for Workplace Health
Pennsylvania Commission on Crime and Delinquency
Drug Enforcement Administration
Substance Abuse and Mental Health Services Administration
Pennsylvania Department of Health
Erie County Government - Drug Services
Centre County Government
Narconon Pennsylvania
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This is by far the easiest way to get my lab work ordered and paid for. The phone calls are short and to the point. They don’t try to push extra sales on you and when I walk in to the clinic I simply show my donor pass and with in a matter of minutes I’m done. I will continue to use ADT in the future.
Jason Jackson - 7/19/2025
Everything was great, the staff was very polite. Thank you.
Olga Petrova - 9/19/2024
The visit here is always the best . The place is always really clean. The employees are super courteous, very polite, and professional. This is the only drug lab I like to go do my drug and alcohol test. I would like to tell them thank you so much for thier excellent performance and job
Eli Gonzalez - 1/4/2025