Our automated scheduling system is available 24/7. Order your test online and receive your donor/registration pass by email. Click Here
Same Day Service
Accredited Drug Testing provides extensive drug and alcohol screening solutions at 39 testing facilities in the Hickory Withe, Tennessee region. Our services cover DOT and non-DOT urine drug tests, breathalyzer alcohol screenings, as well as EtG and hair follicle drug tests, tailored for individuals, businesses, and legal requirements. In Hickory Withe, TN, we ensure quick testing results and SAMSA-certified laboratory evaluations with the convenience of same-day service. Most testing centers are conveniently located within a short distance from your home or workplace. We also offer Occupational Health Assessments, Clinical Tests, and Background Screening Services.
Reach out at (800) 221-4291 or enroll online. Choose your test type and the nearest site—testing is accessible for personal, employee, or third-party needs. Planning a test is Quick and Convenient—contact our scheduling team or arrange your screening online any time, day or night. Our efficient, user-friendly system makes it simple to set up drug testing in Hickory Withe with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Hickory Withe drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Hickory Withe, located in Fayette County, TN, has reported a 15% increase in drug-related arrests over the past year.
Opioid prescriptions in Fayette County, where Hickory Withe is located, are 25% higher than the national average.
In Hickory Withe, TN, over 12% of high school students admit to using illicit drugs within the past 30 days.
Fayette County reported that about 20% of its drug overdose cases come from Hickory Withe.
Hickory Withe, in Fayette County, TN, has seen a 30% rise in the number of people seeking treatment for drug addiction.
Narcan has been administered by first responders in Hickory Withe an average of 10 times per month.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Hickory Withe, TN, are increasingly implementing drug testing policies as part of their employment practices. The Tennessee Department of Labor and Workforce Development (TDLWD) provides guidelines on workplace safety, which include substance abuse policies. Many companies require pre-employment drug tests to ensure a safe working environment.
Some businesses in Hickory Withe also conduct random drug testing to discourage substance abuse among employees. These policies are not only designed to maintain workplace safety but also to identify employees who may need help with addiction issues. Employers often collaborate with local health services for employee assistance programs.
Hickory Withe, TN, collaborates with federal and state agencies to address its drug problems. The Tennessee Department of Mental Health and Substance Abuse Services (TDMHSAS) offers resources for addiction treatment. Locally, efforts are focused on prevention and education through community programs.
The government also supports local law enforcement with grants to combat drug trafficking and abuse. The Substance Abuse and Mental Health Services Administration (SAMHSA) provides guidance and funding to implement evidence-based practices aimed at reducing addiction rates. These joint initiatives aim to create a safer environment for Hickory Withe residents.
Recently, Hickory Withe, TN, has experienced several notable drug-related events. Law enforcement conducted a large drug bust that led to multiple arrests and the confiscation of narcotics. This operation was part of a larger effort by Fayette County law enforcement to curb drug trafficking in the area.
Additionally, community outreach events have been organized to educate residents about the dangers of drug abuse. These events often feature speakers from local and state agencies, aiming to raise awareness and provide resources for those struggling with addiction. Together, these efforts highlight the community's commitment to addressing drug issues head-on.
Accredited Drug Testing offers fast, reliable employment screening services in Hickory Withe, TN. Trusted by employers nationwide for accurate results and exceptional service.
Tennessee DOT/Non DOT Physicals
Tennessee Department of Mental Health and Substance Abuse Services
Tennessee Office of Health Care Statistics
Tennessee Overdose Prevention
Fayette County Mental Health Court
Substance Abuse and Mental Health Services Administration
Tennessee Bureau of Investigation - Drug Investigation Unit
Tennessee Association of Alcohol, Drug & Other Addiction Services
First Step Recovery Centers
Quickly find trusted local drug testing centers in Hickory Withe, TN — fast, convenient, and reliable every time!
Quickly find a local DOT drug testing center in Hickory Withe, TN — fast, reliable, convenient nationwide service!
DNA testing for legal and non-legal purposes including child support, and child custody around Hickory Withe, TN.
Including specimen collector training, DER training, reasonable suspicion training and much more in Hickory Withe, TN.v
Get fast, accurate hair drug testing at our convenient Hickory Withe, TN locations—results you can trust, every time!
Fast, reliable alcohol testing to keep your workplace safe and compliant every single day in Hickory Withe, TN.
Reliable nationwide drug testing services ensuring accuracy, compliance, and quick results for businesses and individuals in Hickory Withe, TN.
Accurate 5 panel drug testing with fast, confidential results—trusted by Hickory Withe, TN employers and individuals nationwide.
Comprehensive 10 panel drug testing with fast, reliable results—trusted for Hickory Withe, TN workplace and personal testing needs.
Convenient on-site mobile drug testing with fast, reliable results—saving time while keeping your Hickory Withe, TN workplace compliant.
Certified DOT physicals with quick, reliable exams to keep Hickory Withe, TN drivers compliant and on the road with confidence.
Join our DOT consortium for hassle-free compliance, random testing management, and reliable driver safety solutions.
Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024