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At Accredited Drug Testing, our 34 testing centers in the Ellendale, Tennessee area deliver a full range of drug and alcohol testing services. We cater to both DOT and non-DOT testing requirements, offering urine drug tests, breath and EtG alcohol tests, alongside hair drug testing options for individual, employer, and legal purposes. Our rapid results service in Ellendale, TN includes SAMSA-certified lab analysis, offering same-day services—all conveniently close to your residence or workplace. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Reach out at (800) 221-4291 or register online; choose your test and select a local center. Testing is designed for personal use, employee assessment, or other individuals. Enjoy the fast, easy process by calling our scheduling team or booking online at any time. With our efficient approach, arranging drug testing near Ellendale becomes a hassle-free experience.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Ellendale drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Ellendale, Shelby County, TN, 15% of high school students reported using illegal drugs in the past year.
Over 200 cases of drug offenses were reported in Ellendale, Shelby County, TN, last year.
Ellendale, Shelby County, TN, saw a 10% increase in drug-related emergency room visits in the last recorded year.
In Ellendale, Shelby County, TN, opioid prescriptions declined by 5% due to stricter regulations.
Shelby County, including Ellendale, TN, reported over 1,000 incidents of drug trafficking in the past 12 months.
Ellendale, Shelby County, TN, has seen a 20% increase in participation in local drug rehabilitation programs.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Ellendale, TN, have adopted stringent drug testing policies to ensure a drug-free workplace. Many businesses require pre-employment drug screenings and conduct random tests to maintain employee safety and productivity. These practices are consistent with Tennessee state regulations, which offer comprehensive guidelines for drug testing in the workplace.
Local employers often collaborate with the Tennessee Bureau of Workers' Compensation (https://www.tn.gov/workforce/injuries-at-work.html) to implement effective drug testing policies. Businesses aim to support employees struggling with substance abuse by offering access to Employee Assistance Programs and referrals to treatment facilities.
The government of Ellendale, TN, in collaboration with Shelby County, is actively addressing drug abuse through various initiatives. Key strategies include enhancing community awareness programs, improving access to treatment, and implementing preventive measures. The county's health department is actively involved in educating the community about the dangers of drug abuse.
Furthermore, Ellendale is working closely with the Tennessee Department of Mental Health and Substance Abuse Services (https://www.tn.gov/behavioral-health) to improve treatment accessibility. Local law enforcement in Ellendale is also participating in state-funded programs designed to reduce drug trafficking and related crimes in Shelby County.
Recent drug busts in Ellendale, TN, highlighted the coordinated efforts of local law enforcement in Shelby County. In a notable event last year, authorities seized over $500,000 worth of illegal drugs, leading to multiple arrests involving a drug trafficking ring. This operation was part of a larger initiative to curb drug-related activities in the area.
Ellendale continues to face challenges with drug-related crimes, but increased police presence and community vigilance have resulted in more successful interceptions and arrests. The Shelby County Sheriff's Office (https://www.shelby-sheriff.org/) actively engages with residents through community events and forums, fostering support and awareness among citizens.
Accredited Drug Testing offers fast, reliable employment screening services in Ellendale, TN. Trusted by employers nationwide for accurate results and exceptional service.
Tennessee DOT/Non DOT Physicals
Tennessee Department of Mental Health and Substance Abuse Services
Substance Abuse and Mental Health Services Administration
Tennessee State Courts - Drug Courts
Tennessee Department of Health - o-drug Strategy
Prevent Substance Abuse NC
U.S. Government Information
Drug Rehab Tennessee
County Health Rankings & Roadmaps
CDC Drug Overdose
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Torin was great. Explained everything so no questions
Tony Lombardo - 4/18/2025
Very easy to get scheduled and easy process once checked in and the staff were all extremely friendly! I would recommend this company!
Ronickia Moore - 11/19/2024
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025