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At our 30 testing centers around Jellico, Tennessee, Accredited Drug Testing delivers an array of thorough drug and alcohol screening services. We cater to DOT and non-DOT urine testing, breathalyzer tests, EtG alcohol analysis, along with hair drug testing, suitable for personal, employer, or legal requirements. Rapid results and SAMSA certified lab evaluations are available in Jellico, TN, with same day service often ready and most centers are conveniently located close to your home or workplace. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Reach us at (800) 221-4291 or register via our website. Select the needed test and a nearby center—our facilities cater to individuals, workforce testing, or testing others. Setting up a test is Quick and Simple, either call our scheduling team or book online anytime. Our seamless, intuitive process makes arranging drug tests close to Jellico hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Jellico drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Jellico, Campbell County, opioid prescriptions are approximately 80% higher than the national average as of 2019.
2018 data shows that Jellico saw a 25% increase in meth-related arrests compared to the previous year.
Hospital reports from 2020 indicate that drug overdoses account for 15% of emergency visits in Jellico, Campbell County.
A 2021 survey found that 10% of high school students in Jellico admit to using illicit drugs.
Jellico experiences higher rates of neonatal abstinence syndrome, with local hospitals reporting a 30% rise from 2017 to 2019.
As of 2022, Jellico, Campbell County reported that 12% of its adult population had substance use disorders.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Jellico, TN, have adopted stringent drug testing policies to maintain a productive work environment. Local industries routinely conduct random drug screenings to deter substance abuse and ensure workplace safety.
These efforts are supported by state regulations and guidance provided by the Tennessee Department of Labor and Workforce Development, emphasizing zero tolerance towards workplace drug abuse.
Additionally, many businesses partner with local rehabilitation centers for training sessions, helping employees understand the adverse effects of drug misuse while providing a resource for those seeking assistance.
The government of Jellico, TN, in collaboration with Campbell County, has actively implemented several programs to address the escalating drug problems. Tennessee Department of Health partners with local organizations to provide necessary tools and strategies.
Federal efforts, like those administered by the Substance Abuse and Mental Health Services Administration, aim to reduce drug abuse by offering grants for community support programs, educational workshops, and addiction treatment services in the area.
Jellico, TN, in Campbell County, has witnessed several significant drug-related incidents. In 2021, law enforcement agencies conducted a major drug bust, seizing large quantities of methamphetamine and resulting in multiple arrests.
Locally organized drug awareness events are regularly held, often backed by community organizations and supported by the Campbell County Sheriff's Office. These events aim to educate the public and reduce drug-related crimes.
In the summer of 2023, a collaboration between local police and the Tennessee Bureau of Investigation led to a crackdown on a drug trafficking ring operating out of Jellico, further showcasing the town's commitment to addressing its drug problem.
Accredited Drug Testing offers fast, reliable employment screening services in Jellico, TN. Trusted by employers nationwide for accurate results and exceptional service.
Tennessee DOT/Non DOT Physicals
Tennessee Association of Alcohol, Drug & other Addiction Services (TAADAS)
The Campbell County Government
Tennessee Department of Mental Health
Cumberland Health Care Group
Healing Housing
Cornerstone Recovery
Mental Health Association of East Tennessee
Tennessee Bureau of Investigation
TN Department of Health: Jackson Area Indian Birth Health
National Association for the Dually Diagnosed
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024