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Accredited Drug Testing provides a range of drug and alcohol testing services at our 35 facilities in the Kimball, Tennessee region. We facilitate both DOT and non-DOT urine analyses, breathalyzer tests, EtG alcohol assessments, and hair follicle drug screenings for personal, occupational, and legal purposes. In Kimball, TN, we ensure expedited test results and laboratory evaluations accredited by SAMSA. Same-day testing services are accessible, with most locations being conveniently located just moments from your residence or office. Additionally, we offer Occupational Health Evaluations, Clinical Screenings, and Background Verification Services.
For test registration, dial (800) 221-4291 or visit our website to register online. You simply need to select the desired test and the most convenient testing site—available for you, employees, or others. Our process is quick and efficient; you can coordinate with our scheduling team or book online at any time. Our seamless system simplifies setting up drug tests in Kimball.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Kimball drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In recent years, Kimball, TN, located in Marion County, has seen an increase in drug-related arrests by 15%.
Kimball in Marion County reported that drug-related emergency room visits have increased by 20% in the past two years.
A survey in Kimball noted that 7% of high school students in Marion County admitted to using illicit drugs.
Over 60% of arrests in Kimball are associated with drug offenses, according to Marion County statistics.
Marion County health officials noted that opioid prescriptions in Kimball have decreased by 10% in the last year.
Treatment admissions for drug abuse in Kimball's Marion County have risen by 5% over the past two years.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Kimball, TN, are increasingly adopting strict drug testing policies as a part of their employment practices. Many businesses mandate pre-employment drug screenings in an effort to create a safe and productive work environment, in line with guidelines from the Tennessee Department of Labor and Workforce Development.
In Marion County, larger companies often conduct random drug tests to deter substance abuse among employees. Companies are aware of the impact drug abuse can have on productivity and safety, making compliance with federal regulations a priority. For detailed information on workplace safety related to substance abuse, you can visit the Occupational Safety and Health Administration (OSHA) website.
The government of Kimball, TN, in collaboration with Marion County, has intensified its efforts to combat drug abuse through various initiatives. This includes increased funding for addiction treatment centers and awareness programs in local communities. The Tennessee State Government works closely with local authorities to implement these programs effectively.
Law enforcement agencies in Marion County are also part of a statewide network focused on reducing drug-related crimes. The state provides resources and training for local police to better handle drug-related incidents. Information on these initiatives can be found at the Tennessee Department of Mental Health and Substance Abuse Services website.
Recently, law enforcement in Kimball, TN, staged a significant drug bust that led to the arrest of several individuals involved in a multi-county drug distribution ring. The operation involved the collaboration of state and federal agencies and highlighted the growing concern over drug trafficking in Marion County.
Kimball has also hosted numerous community events aimed at raising awareness and providing education on the risks of drug abuse. These include workshops and forums backed by local organizations and supported by the Marion County Health Department, aiming to keep the community informed and engaged in drug prevention efforts.
Accredited Drug Testing offers fast, reliable employment screening services in Kimball, TN. Trusted by employers nationwide for accurate results and exceptional service.
Tennessee DOT/Non DOT Physicals
Tennessee Courts
TN Department of Mental Health
TN Department of Health
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Tennessee DOT
Metro Drug Coalition
Stop Addiction
Narcotics Anonymous
SAMHSA
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024