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Accredited Drug Testing provides a wide array of drug and alcohol screening services at 31 convenient locations around Lancaster, Virginia. We offer both DOT and non-DOT urine drug testing, breath alcohol tests, EtG alcohol assessments, and hair drug screens suitable for personal, employment, or legal purposes. With fast testing and SAMSA-certified lab analysis, same-day service is often available, and most facilities in Lancaster, VA are easily accessible from your home or workplace. Other services offered include Occupational Health Testing, Clinical Testing, and Background Checks.
To get started, call (800) 221-4291 or register online. Pick your preferred test and location, which can be for yourself, an employee, or another party. The scheduling process is quick and straightforward—contact our scheduling team or book online anytime. Our efficient and intuitive system makes drug testing arrangements near Lancaster a breeze.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Lancaster drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Lancaster County, VA, approximately 10% of the population reported illicit drug use in the past year.
Lancaster, VA has seen a 25% increase in drug-related overdoses over the past three years.
Lancaster County ranks within the top 10 counties in Virginia for highest opioid prescription rates.
Surveys indicate that 15% of high school students in Lancaster, VA, have used prescription drugs without a doctor's prescription.
The rate of emergency room visits in Lancaster County for drug-related issues has doubled since 2018.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Lancaster, VA, are increasingly aware of the impact of drug abuse on the workforce and have implemented drug testing policies to ensure a safe working environment. Many businesses conduct pre-employment screenings and random drug tests to deter substance use and maintain productivity. Policies are guided by standards set by the U.S. Department of Labor.
Local companies aim to support employees by offering access to employee assistance programs (EAPs) that provide confidential counseling and rehabilitation services. Through partnerships with healthcare providers, these programs assist employees in managing addiction and related issues, reinforcing the importance of a drug-free workplace within Lancaster County.
The government of Lancaster, VA, is actively working to combat drug issues through various programs and partnerships. The Virginia State Government has implemented statewide initiatives focused on reducing opioid misuse by increasing access to treatment and prevention resources. In collaboration with local stakeholders, Lancaster County aims to promote community awareness and education about substance abuse.
The Lancaster County Health Department plays a crucial role in addressing drug abuse by offering resources and support to affected individuals. Local law enforcement works in conjunction with state agencies to reinforce anti-drug laws and facilitate rehabilitation over incarceration. More information about state efforts can be found on the Department of Social Services website.
Recent drug busts in Lancaster, VA, have highlighted the ongoing battle against narcotics distribution in the area. In 2023, a major operation led by the county's law enforcement resulted in the seizure of large quantities of opioids and arrests of multiple suspects, showcasing the dedication of local authorities in combating drug-related crime.
Community events organized by local nonprofits and public health offices aim to educate residents on the dangers of drug abuse and prevention strategies. These include workshops and seminars held at community centers to engage and inform Lancaster's populace, fostering a proactive approach to tackling substance abuse issues.
Accredited Drug Testing offers fast, reliable employment screening services in Lancaster, VA. Trusted by employers nationwide for accurate results and exceptional service.
Virginia Prevention Works
Faces & Voices of Recovery
Substance Abuse Free Lancaster
Virginia Department of Health
Virginia Recovery Programs
Lancaster Community Library
New Kent County Resources
Central Atlantic Counseling & Treatment
Community Focus Virginia
Virginia Addiction, Drug, and Rehab Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024