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Accredited Drug Testing provides an extensive array of drug and alcohol testing options at our 40 centers located in the Norfolk, Virginia area. Whether for DOT compliance or general purposes, we conduct urine and hair drug tests, as well as breath alcohol and EtG alcohol assessments for individual, employment, and legal requirements. In Norfolk, VA, expedited testing results and SAMSA-certified lab analyses are available, offering same-day services with most centers conveniently located close to your residence or workplace. Our additional offerings include Occupational Health Testing, Clinical Testing, and Background Checks.
To schedule, call (800) 221-4291 or register via our website. Just pick your test and find a nearby center—testing can be arranged for yourself, employees, or others. Arrange your test swiftly by contacting our scheduling team or book online at any time. Our efficient, user-friendly system makes setting up drug testing in Norfolk simple and stress-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Norfolk drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2020, Norfolk, VA, saw 120 opioid-related overdose deaths, reflecting a troubling trend in the city.
The city of Norfolk, within Norfolk County, reported over 1,500 drug-related arrests in 2021.
In 2019, approximately 7.8% of Norfolk, VA residents reported illicit drug use according to state surveys.
Norfolk General Hospital treated 300+ individuals for drug overdoses in 2021, marking a rise from previous years.
In Norfolk, VA, drug-related criminal cases constitute 20% of the local court docket, highlighting the issue.
Norfolk, VA, implemented over 50 community outreach programs in 2022 aimed at reducing drug misuse.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Norfolk, VA often incorporate drug testing policies as part of their employment criteria. These policies are influenced by guidelines from the U.S. Department of Labor, ensuring workplace safety and compliance. Pre-employment testing is a common practice among top employers.
Additionally, random drug testing policies are employed by organizations to deter workplace drug use. This approach helps maintain productivity and safety, aligning with Virginia state laws regarding substance abuse in the workplace.
Norfolk, VA actively engages in combating drug issues with initiatives hosted by the Norfolk Department of Public Health. The city collaborates with local and state agencies to offer education and resources aimed at reducing substance abuse.
Efforts are also supported by the Virginia Department of Health, which provides funding for local prevention programs. The city focuses on prevention, treatment, and law enforcement to combat the drug epidemic.
Norfolk, VA has witnessed several significant drug busts, underscoring the persistent challenge of combating drug trafficking. In early 2023, Norfolk authorities, in collaboration with federal agencies, dismantled a major drug distribution network, leading to multiple arrests.
Local law enforcement frequently conducts operations focused on reducing street-level drug sales. These efforts have resulted in the confiscation of substantial quantities of illegal substances, demonstrating Norfolk's commitment to tackling drug crime.
Accredited Drug Testing offers fast, reliable employment screening services in Norfolk, VA. Trusted by employers nationwide for accurate results and exceptional service.
Virginia Harm Reduction Coalition
Virginia Phoenix
Valley Health
Virginia Department of Behavioral Health and Developmental Services
Substance Abuse and Mental Health Services Administration
Norfolk Housing Outreach
Carilion Clinic
The o-drug Library
Quickly find trusted local drug testing centers in Norfolk, VA — fast, convenient, and reliable every time!
Quickly find a local DOT drug testing center in Norfolk, VA — fast, reliable, convenient nationwide service!
DNA testing for legal and non-legal purposes including child support, and child custody around Norfolk, VA.
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Quick, knowledgeable and courteous Janelle worked diligently to support me. I am recommending their services to anyone looking.
Greensboro Joseph - 11/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
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Yusuf Narmuradov - 11/19/2024