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Accredited Drug Testing delivers an extensive array of drug and alcohol examinations through our 35 testing facilities around New Berlin, Pennsylvania. Our services cover DOT and non-DOT urine analyses, breath alcohol measurements, EtG alcohol assessments, and hair-based narcotic screenings for private individuals, companies, and legal entities. In New Berlin, PA, we ensure swift testing results and offer SAMSA-certified lab analysis, with same-day appointments readily available. Most testing sites are conveniently located minutes from your residence or workplace. We also provide Occupational Health Evaluations, Clinical Assessments, and Background Verification services.
Contact us at (800) 221-4291 or register through our website. Choose your desired test and select a nearby site—facilities cater to you, your staff, or another person. Arranging a test is Quick and Straightforward, with the option to contact our scheduling team or utilize our online booking system any time. Our efficient and accessible service makes coordinating drug tests in New Berlin a breeze.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our New Berlin drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In New Berlin, PA, Union County, opioid-related overdose deaths have seen a 12% increase in the past year, highlighting a growing crisis.
Union County ranks fifth in Pennsylvania for per capita prescription opioid sales, affecting New Berlin significantly.
In New Berlin, Union County, the number of individuals seeking treatment for heroin abuse rose by 10% in the last fiscal year.
New Berlin, situated in Union County, reported that 15% of high school students admitted to illicit drug use in a 2022 survey.
Union County, encompassing New Berlin, has seen a 30% rise in emergency room visits for drug overdoses over the last year.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in New Berlin, PA, have adopted stringent drug testing policies to ensure a safe workplace environment. Many businesses implement pre-employment testing and random drug tests to deter drug use. This approach aligns with the guidelines from the Substance Abuse and Mental Health Services Administration (SAMHSA), promoting a drug-free workplace.
Additionally, businesses in New Berlin collaborate with local law enforcement agencies to stay informed about drug trends and ensure compliance with state laws. Employers are encouraged to refer employees struggling with addiction to appropriate resources, creating a supportive yet disciplined work atmosphere.
The government of New Berlin, PA, in Union County has been actively working to combat drug abuse through various initiatives. Collaboration with agencies like the Pennsylvania Department of Drug and Alcohol Programs has been significant in addressing these challenges. They have also increased funding for local rehabilitation centers and prevention programs to minimize drug addiction issues in the community.
Efforts specifically targeting opioid addiction have been a focus in Union County, with the introduction of educational campaigns and support for healthcare providers prescribing opioids. The partnership with the Centers for Disease Control and Prevention (CDC) aims to reduce prescription drug misuse through monitoring and regulatory measures.
In recent years, New Berlin, PA, has experienced several notable local drug busts. Authorities in Union County successfully dismantled a significant drug trafficking ring in late 2022, seizing large quantities of opioids and other illicit substances. This operation significantly reduced the local supply of illegal drugs and was led by the Union County Drug Task Force.
Additionally, community events such as drug take-back days have been organized in New Berlin, allowing residents to safely dispose of unused prescription medications. These events aim to prevent misuse and are often coordinated by local police departments in association with national initiatives.
Accredited Drug Testing offers fast, reliable employment screening services in New Berlin, PA. Trusted by employers nationwide for accurate results and exceptional service.
Pennsylvania DOT/Non DOT Physicals
Pennsylvania o-drug Data Dashboard
Get Help Now - DDAP
PA Department of Health - Treatment
Recovery.org Resources for Pennsylvania
NARCAN®︎ Nasal Spray
SAMHSA National Helpline
Union County Drug and Alcohol Services
Crisis Text Line
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024