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Accredited Drug Testing supplies all-inclusive substance analysis services at 32 testing sites in the Germantown, Tennessee vicinity. Catering to DOT and non-DOT regulations, we administer urine drug evaluations, breath alcohol assessments, EtG alcohol screenings, and follicle substance evaluations for personal, corporate, and judicial purposes. In Germantown, TN, we feature expedited testing with certified SAMSA lab processing, offering same-day results; most locations are conveniently near your residence or workplace. Other provisions include Occupational Health Evaluations, Clinical Analysis, and Background Verifications.
Dial (800) 221-4291 or register digitally. Pick your desired evaluation and a close venue—testing is open for you, your staff, or others. Setting up a test is Quick and Simple; communicate with our scheduling team or organize your evaluation online anytime, 24/7. Our simplified and accessible process ensures easy coordination for drug tests near Germantown without hassle.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Germantown drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Germantown, within Shelby County, drug-related arrests increased by 15% from 2020 to 2022.
Shelby County, including Germantown, reported a 10% rise in opioid overdose deaths in 2021.
Germantown high schools witnessed a 5% increase in student drug-related incidents in 2022.
Shelby County authorities confiscated 20% more illegal substances from Germantown in 2022 compared to 2021.
In 2021, 8% of Shelby County emergency room visits from Germantown involved drug overdoses.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Germantown, TN are increasingly implementing strict drug testing policies to maintain safe workplace environments. Many follow guidelines provided by the Tennessee Department of Labor and Workforce Development to ensure compliance with state and federal regulations.
Larger organizations may conduct regular drug screenings as a part of their employment process, while smaller companies in Germantown often opt for random drug testing to deter drug use among employees. These efforts align with broader community initiatives to reduce drug-related issues, helping to maintain public safety in the workplace.
The government of Germantown, TN, has been proactive in addressing drug problems through local initiatives and partnerships. Shelby County has implemented programs focusing on education and prevention of drug abuse. A key resource is Shelby County's official website where residents can find detailed information on current initiatives and support programs.
State-level collaboration also plays a significant role, with Tennessee's ongoing campaigns to mitigate drug-related issues evident through state behavioral health services. Joint tasks forces and community programs focus on reducing opioid addiction and offering rehabilitation services across Shelby County, including Germantown.
The Germantown Police Department recently executed a significant drug bust in collaboration with surrounding local agencies. Acting on a tip-off, they uncovered a network involved in the distribution of illegal substances. The operation lasted several months, with undercover officers gathering crucial evidence that led to multiple arrests.
In another event, a routine traffic stop resulted in the discovery of a large quantity of illegal drugs concealed within the vehicle. The driver, a resident of Germantown, was taken into custody and is now facing several charges including possession with intent to distribute. The incident highlights the ongoing efforts of local law enforcement to combat drug-related activities in the area.
Community members are urged to remain vigilant and report any suspicious activities to the authorities. Initiatives such as neighborhood watches and educational programs in schools are being implemented by the city to help prevent drug misuse and abuse among the youth. These proactive steps aim to create a safer environment for all Germantown residents.
Accredited Drug Testing offers fast, reliable employment screening services in Germantown, TN. Trusted by employers nationwide for accurate results and exceptional service.
Tennessee DOT/Non DOT Physicals
Tennessee Department of Mental Health and Substance Abuse Services
Tennessee Suicide Prevention Network
Shelby County's Official Website
Memphis Recovery Centers
Treatment Centers Directory - Tennessee
Cumberland Heights - Nashville, TN
Cornerstone of Recovery - Knoxville, TN
The Hope Center - Union City, TN
Integrative Life Center - Nashville, TN
Whiteside Recovery Systems - Memphis, TN
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024