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At 30 different testing sites in Waianae, Hawaii, Accredited Drug Testing provides all-encompassing drug and alcohol testing solutions. We conduct DOT and non-DOT urine analyses, breath alcohol assessments, EtG tests for alcohol, and hair drug screenings for personal, employer, or legal purposes. Rapid test results and SAMSA certified lab analyses are available, with many Waianae centers just minutes from your home or workplace. We also perform Occupational Health Testing, Clinical Services, and Background Verifications.
Dial (800) 221-4291 or use our online registration. You can easily select your test and choose a nearby facility. Tests can be scheduled for yourself, employees, or others. Fast and efficient test scheduling is available anytime via phone or online 24/7. Our simple process allows seamless arrangement of drug testing close to Waianae.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Waianae drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, 15.7% of Waianae's residents reported illicit drug use within the past year, according to data from Honolulu County.
Honolulu County reported over 800 drug-related arrests in Waianae in 2021, a significant increase from previous years.
The rate of opioid prescribing in Waianae, Honolulu County, saw a 5% decline from 2019 to 2021, according to health department reports.
A study found that drug overdose deaths in Waianae accounted for 12% of all such deaths in Honolulu County in 2020.
In 2020, methamphetamine was involved in 62% of drug-related incidents reported in Waianae, Honolulu County.
Waianae sees significant representation in Honolulu County's drug treatment admissions, comprising nearly 18% annually.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
In Waianae, HI, employers are increasingly adopting strict drug testing policies to maintain workplace safety and productivity. The Hawaiian Electric Company, for example, implements random drug testing procedures aligned with guidelines provided by the Occupational Safety and Health Administration.
Several local businesses partner with the Hawaii State Department of Health to develop comprehensive drug-free workplace programs, which include employee education, counseling resources, and access to local treatment facilities.
Government efforts in Waianae, HI, focus on tackling the drug problem through education, prevention, and rehabilitation programs. The Hawaii State Department of Health plays a crucial role in orchestrating community outreach initiatives and support services aimed at reducing drug abuse.
The Honolulu County government collaborates with state authorities to enhance law enforcement strategies against drug trafficking. Agencies like the Hawaii Police Department receive federal support to strengthen their resources and conduct community policing.
In a recent significant event in Waianae, HI, local authorities conducted a coordinated drug bust operation. This operation was part of a larger initiative to curb the flow of illegal substances in the region. Multiple arrests were made, and a noteworthy quantity of methamphetamine was seized, reflecting ongoing efforts to dismantle networks involved in drug distribution.
Community leaders in Waianae have expressed their support for the recent law enforcement actions targeting drug-related activities. The collaborative efforts between local residents and police aim to create a safer environment for all. Through these joint operations, there is a concerted push to address the drug issues that have impacted the area significantly.
In another related event, the Waianae police department launched a series of community outreach programs focused on drug prevention and education. These programs are designed to raise awareness about the dangers of drug use and provide resources for individuals seeking help. The initiative highlights a preventative approach by engaging youth and parents in open discussions about the risks associated with drugs.
Accredited Drug Testing offers fast, reliable employment screening services in Waianae, HI. Trusted by employers nationwide for accurate results and exceptional service.
Hawaii State Department of Health
Hawaii Police Department
Pacific Alliance to Stop Abuse and Addiction
Hawaii o-drug Initiative
Hawaii Substance Abuse Prevention, Treatment & Recovery
Coalition for a Drug-Free Hawaii
Asian American Pacific Islander Health Forum
Malama Na Makua A Keiki
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025